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The fragrance facts, graded

Every fact on this site, with its evidence grade, its caveats, and a link to the source.

We start you on the strong ones: findings that have been replicated or come from one large, well-controlled study. Moderate and weak facts are here too, labeled for what they are. Use “Link to this fact” to share a single card.

2 facts match “phthalate”

Children and pregnancy / Measured in people or real products

Pregnant women who had used perfume or cologne in the past day had 167% higher urine levels of MEP, the breakdown product of the fragrance solvent diethyl phthalate (DEP), than women who hadn't (177 women, Boston).

Strong evidence.

Caveats

Exposure marker, not health outcome; independently replicated in two further US cohorts with overlapping confidence intervals: Parlett 2013 (2.92x, postpartum, SFF multi-site) and Just 2010 (2.3x, 95% CI 1.6-3.3, pregnant, NYC minority cohort, with a dose-response and a null personal-air DEP association pointing to a dermal exposure route).

Source: Braun 2014, Journal of Exposure Science and Environmental Epidemiology Link to this fact

Children and pregnancy / Review of other studies

A 2018 US EPA systematic review found robust evidence that two common phthalates, DEHP and DBP, are linked to male reproductive harm (lower sperm quality; shorter anogenital distance in baby boys exposed before birth) at everyday exposure levels.

Strong evidence: Associations graded by protocol; DEHP/DBP are mainly plasticizers, not fragrance ingredients; no meta-analysis.

Source: Radke 2018 (US EPA), Environment International Link to this fact

Information, not medical advice. See also: myths we won’t tell you.