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The fragrance facts, graded

Don’t take our word for it. Here’s every fact on this site, with its evidence grade, its caveats, and a link to the source, so you can check us.

We start you on the strong ones: findings that have been replicated or come from one large, well-controlled study. Moderate and weak facts are here too, labeled for what they are. Use “Link to this fact” to share a single card.

17 facts match “cleaning”

Children and pregnancy / Measured in people or real products

In 34 California childcare centers, the chemicals at the highest levels in the air children breathed came from cleaning and personal-care products: a silicone ingredient called D5 (median 51 µg/m³) and the citrus-scent chemical limonene (median 33 µg/m³).

Strong evidence: Single-day samples; upper values capped by calibration (underestimates).

Source: Hoang 2016, Indoor Air Link to this fact

Children and pregnancy / Review of other studies

Children exposed to household chemical/cleaning products before birth or in their first year wheeze more often, now replicated in four independent prospective birth cohorts. The founding ALSPAC cohort (UK, n=7,019, Sherriff et al. 2005) found that an 11-product, frequency-weighted prenatal household chemical (TCB) score was significantly associated with persistent wheeze through 3.5 years (adjusted OR 1.06 per unit increase; top-vs-bottom-decile adjusted OR 2.3), but not with transient early or late-onset wheeze; this is the same ALSPAC cohort and composite-score methodology that both Casas 2013 and Mikeš 2019 name as their model. In the Canadian CHILD cohort (n=2,022), frequent use in early infancy was linked to higher odds of recurrent wheeze (adjusted OR 1.35) and asthma diagnosis (adjusted OR 1.37) by age 3, but not isolated skin-prick allergy (adjusted OR 1.14, ns), though wheeze combined with allergy was itself raised (adjusted OR 1.49). In the Czech ELSPAC-CZ cohort (n=3,411), each 1-SD increase in an 18-product household chemical exposure score at 6 months raised the odds of intermediate-onset transient, intermediate-onset persistent, and early-onset persistent wheeze phenotypes through age 5 (adjusted OR 1.23-1.36), and those persistent phenotypes carried 5-8x higher odds of doctor-diagnosed asthma at age 7 (pediatrician records, not self-report). In the pooled Spanish INMA cohorts (n=2,292), prenatal (third-trimester) use of cleaning sprays raised the odds of both wheezing (OR 1.37) and lower respiratory tract infection (OR 1.29) in the first year of life, with solvents raising wheezing odds (OR 1.30) and air fresheners raising LRTI odds (OR 1.29); bleach, ammonia, and non-spray cleaners showed no association.

Strong evidence.

Caveats

All four cohorts are observational and use self-reported product-use frequency, not measured indoor air chemistry. The ALSPAC/Sherriff 2005 and ELSPAC-CZ signals are specific to persistent-type wheeze phenotypes, not wheeze in general; ALSPAC found no association with transient early or late-onset wheeze. The 'not atopy' finding remains single-cohort (CHILD only); ELSPAC-CZ's atopic-rash variable is a covariate, not an outcome, and Casas 2013 measured neither atopy nor a physician asthma diagnosis, only maternal-reported LRTI and any-wheezing through 12-18 months, so it neither confirms nor refutes the atopy finding; ALSPAC/Sherriff 2005 did not assess atopy or asthma at all. Casas 2013 is the only cohort among the three post-2010 cohorts with genuinely prenatal (rather than early-postnatal) exposure measurement, but ALSPAC/Sherriff 2005 is also prenatal and its composite score behaved like CHILD's and ELSPAC-CZ's (significant), not like Casas's (null) — evidence against prenatal timing per se explaining the Casas null. Casas 2013's own summed cleaning-product-count score was NOT a significant predictor, unlike ALSPAC's, CHILD's, and ELSPAC-CZ's frequency-weighted composite scores — an open methodological tension (register entry C262) that means 'more products used' is not yet a uniformly replicated exposure metric across all cohorts, even though several specific products (sprays consistently, plus solvents and air fresheners) are.

Source: Salonen 2024, Environment International Link to this fact

Children and pregnancy / Measured in people or real products

In a national Canadian birth cohort (n=2,022), infants in homes with more frequent use of household cleaning products at 3–4 months of age had higher odds of recurrent wheeze (adjusted OR 1.35 per interquartile increase in use) and of an asthma diagnosis (adjusted OR 1.37) by age 3, but no higher odds of isolated allergic sensitization (skin-prick positivity).

Strong evidence.

Caveats

Observational; the authors explicitly state their results do not prove causation. Recurrent wheeze combined with atopy was itself significantly increased (adjusted OR 1.49), so isolated atopy — not allergic sensitization in general — is what showed no association.

Source: Parks et al. 2020, CMAJ (Canadian Medical Association Journal) Link to this fact

Green, natural and unscented / Other evidence

EWG Verified does not mean fragrance-free: fragranced cleaners can be licensed with fragrance up to 1 percent of the formula.

Strong evidence: Pet grooming products are limited to an EWG 'acceptable fragrance list' not reproduced in the document.

Source: EWG Verified criteria for cleaning products (10.24), Environmental Working Group, 2024 Link to this fact

Hidden ingredients / Other evidence

For EWG Verified cleaners whose fragrance has more than five ingredients, the package may show only 'fragrance*' plus the first five; the full list is online.

Strong evidence: Describes the rule as written; no data on how many licensed products use the shortened form.

Source: EWG Verified criteria for cleaning products (10.24), Environmental Working Group, 2024 Link to this fact

Indoor air / Review of other studies

A chemical released indoors is roughly 1,000 times more likely to be breathed in than the same amount released outdoors (exact when comparing the low end of each range; only ~100x at the high end, since the ranges overlap at 10⁻³), so cleaning products and air fresheners (about 1% of California's smog-forming emissions) may deliver an inhaled dose on the same scale as all outdoor sources combined.

Strong evidence.

Caveats

Modeled population intake fractions (not measurements), population-average estimate. Traced to the primary source, Lai, Thatcher & Nazaroff 2000 (JAWMA 50:1688-1699), which derives outdoor PITF 10⁻⁶-10⁻³ vs indoor/in-vehicle PITF 10⁻³-10⁻¹ from Gaussian-plume and mass-balance modeling (Nazaroff co-author of both papers, so this is not independent replication). The ranges overlap at 10⁻³, so '1000x' is a floor-to-floor comparison, not a fixed multiplier under all conditions.

Source: Nazaroff & Weschler 2004, Atmospheric Environment Link to this fact

Indoor air / Review of other studies

Scent chemicals such as limonene and pine oil react with ozone indoors to make new pollutants, including formaldehyde and fine particles, that keep forming for hours after cleaning ends.

Strong evidence: Size of the effect depends on dose and indoor ozone; confirmed by later chamber and field studies.

Source: Nazaroff & Weschler 2004, Atmospheric Environment Link to this fact

Indoor air / Measured in people or real products

Questionnaires about habits and routines correctly sorted only 20% of people by their measured exposure to cleaning and fragrance chemicals, vs 61% for traffic fumes; exposure depends on individual behavior and product choice.

Strong evidence.

Caveats

'Product choice' is the authors' explanation, not directly tested in this paper; independently corroborated by a larger, more direct 2021 UK study (Heeley-Hill 2021, 60 homes, daily diary-logged — not recalled — product-use frequency vs measured concentrations) that found cumulative product-use frequency has essentially no predictive power for measured indoor VOC concentrations (R²<0.001 for total VOC; no individual VOC significant).

Source: Edwards 2006, Atmospheric Environment Industry-funded Link to this fact

Indoor air / Measured in people or real products

In week-long air measurements across 11 European cities, the scent chemicals limonene and alpha-pinene were the compounds most concentrated in homes compared with workplaces (about 4x), attributed to perfumes, cleaning and fragranced products.

Strong evidence: Source attribution by the authors, not measured per product.

Source: Geiss 2011, Atmospheric Environment Link to this fact

Indoor air / Measured in people or real products

Scent-type chemicals typical of fragranced and cleaning products (limonene, pinene, carene) were the signature of home air: close to zero outdoors but tens to hundreds of times higher inside homes.

Strong evidence.

Caveats

Small original study (n=7); the indoor-source signature (not the specific product-category attribution) is now independently replicated by a much larger 2021 UK study with real paired outdoor sampling (Heeley-Hill 2021, 60 homes: limonene indoor:outdoor ~19x, alpha-pinene ~10x), though that larger study also found cumulative product-use frequency does not predict concentration (only insecticide/plug-in-air-freshener use showed weak covariance with limonene) — so the indoor-source signature is strong, the specific 'cleaning products' attribution stays inferential. Givaudan-funded (COI); analysis independent.

Source: Gokhale 2008, Science of the Total Environment Link to this fact

The industry / Other evidence

EWG Verified is a licensing program in which EWG writes the criteria, scores the products, pre-approves the mark's use in marketing, and can bar claims that 'would harm or discredit EWG'.

Strong evidence: EWG is an advocacy nonprofit, not an industry body, but it is an interested party acting as standard-setter, certifier and publisher.

Source: EWG Verified criteria for cleaning products (10.24), Environmental Working Group, 2024 Link to this fact

Laws and loopholes / Government agency

The 2022 US cosmetics law does not cover air fresheners, cleaning products, or laundry products at all.

Strong evidence: MoCRA amends the FFDCA cosmetics chapter only; household products fall under CPSC/EPA law.

Source: MoCRA 2022 Link to this fact

Laws and loopholes / Other evidence

FDA's food allergen labeling law explicitly does not apply to cosmetics, drugs, or household cleaning products, so fragrance allergens in those products have no allergen-naming duty under it.

Strong evidence: Says nothing about the separate MoCRA fragrance-allergen rulemaking, which is still pending.

Source: FDA food allergen Q&A Ed. 5 (2025), FDA guidance for industry (Docket FDA-2022-D-0099) Link to this fact

Laws and loopholes / Other evidence

OSHA lists perfumes and colognes, cleaning products, pesticides and personal-care products among sources of workplace indoor air pollutants, but sets no limit or rule for any of them.

Strong evidence: Mentions are brief source lists; fragrance is not named as a category, and no health data are given.

Source: OSHA 3430-04, 2011 Link to this fact

Skin allergy / Measured in people or real products

In a clinical study of 658 hand-eczema patients across 3 European centers, 67 (10.2%) reacted on patch testing to at least one fragrance chemical selected because it is common in household cleaning and personal-care products used on the hands.

Strong evidence: Clinic-referred hand-eczema population (3 tertiary centers), not a random sample of the general public.

Source: Heydorn 2003, Contact Dermatitis Industry-funded Link to this fact

What you can do / Government agency

EPA says to never mix chlorine bleach solution with other cleaning solutions or detergents that contain ammonia, because toxic fumes could be produced.

Strong evidence: Well-established chemistry (chloramine gas formation); stated here as a direct safety instruction, not a study finding.

Source: US EPA, "A Brief Guide to Mold, Moisture and Your Home" Link to this fact

What you can do / Other evidence

EWG will not license air fresheners, candles, plug-in or timed-release odor products, or liquid laundry and dishwasher pods, so an EWG Verified mark will not be found on those product types.

Strong evidence: Reflects the 10.24 criteria; EWG may change categories, and unlicensed products are not necessarily worse.

Source: EWG Verified criteria for cleaning products (10.24), Environmental Working Group, 2024 Link to this fact

Information, not medical advice. See also: myths we won’t tell you.