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The fragrance facts, graded

Don’t take our word for it. Here’s every fact on this site, with its evidence grade, its caveats, and a link to the source, so you can check us.

We start you on the strong ones: findings that have been replicated or come from one large, well-controlled study. Moderate and weak facts are here too, labeled for what they are. Use “Link to this fact” to share a single card.

1 facts match “isomethyl”

Fragrance is everywhere / Measured in people or real products

Besides the fragrance-mix allergens, 14 other common fragrance materials (including linalool, benzyl acetate, and hedione) were found in 40-97% of the 73 deodorants tested in 1996; for three of them (hedione, linalyl acetate, alpha-isomethyl ionone) no published human contact-allergy case existed at the time despite their widespread use.

Moderate evidence.

Caveats

Absence of published reports as of 1998 is not the same as absence of risk; testing history for these three substances specifically was not systematically reviewed by the authors beyond a literature check.

Source: Rastogi et al. 1998, Contact Dermatitis Link to this fact

Information, not medical advice. See also: myths we won’t tell you.